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Opiate use inhibits TLR9 signaling pathway in vivo: possible role in pathogenesis of HIV-1 infection

The molecular mechanism of opiate use promoting HIV-1 infection is not fully understood. TLR9 is expressed in many immune cells, including monocytes, macrophages, which can recognize viruses and viral products and consequently induce the production of antiviral factors and initiate immune responses....

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Detalles Bibliográficos
Autores principales: Liao, Yanyan, Jiang, Junjun, Liang, Bingyu, Wei, Fumei, Huang, Jiegang, Pan, Peijiang, Su, Jinming, Zhou, Bo, Zang, Ning, Ye, Li, Liang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638828/
https://www.ncbi.nlm.nih.gov/pubmed/29026137
http://dx.doi.org/10.1038/s41598-017-12066-3