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Opiate use inhibits TLR9 signaling pathway in vivo: possible role in pathogenesis of HIV-1 infection
The molecular mechanism of opiate use promoting HIV-1 infection is not fully understood. TLR9 is expressed in many immune cells, including monocytes, macrophages, which can recognize viruses and viral products and consequently induce the production of antiviral factors and initiate immune responses....
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638828/ https://www.ncbi.nlm.nih.gov/pubmed/29026137 http://dx.doi.org/10.1038/s41598-017-12066-3 |