Essential role of the Na(+)-Ca2(+) exchanger (NCX) in glutamate-enhanced cell survival in cardiac cells exposed to hypoxia/reoxygenation

Myocardial ischemia culminates in ATP production impairment, ionic derangement and cell death. The provision of metabolic substrates during reperfusion significantly increases heart tolerance to ischemia by improving mitochondrial performance. Under normoxia, glutamate contributes to myocardial ener...

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Detalles Bibliográficos
Autores principales: Maiolino, Marta, Castaldo, Pasqualina, Lariccia, Vincenzo, Piccirillo, Silvia, Amoroso, Salvatore, Magi, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638850/
https://www.ncbi.nlm.nih.gov/pubmed/29026150
http://dx.doi.org/10.1038/s41598-017-13478-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638850/
https://www.ncbi.nlm.nih.gov/pubmed/29026150
http://dx.doi.org/10.1038/s41598-017-13478-x

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