MCPH1, mutated in primary microcephaly, is required for efficient chromosome alignment during mitosis

MCPH1 gene, mutated in primary microcephaly, regulates cell progression into mitosis. While this role has been extensively investigated in the context of DNA damage, its function during unperturbed cell cycles has been given less attention. Here we have analyzed the dynamics of chromosome condensati...

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Detalles Bibliográficos
Autores principales: Arroyo, M., Kuriyama, R., Trimborn, M., Keifenheim, D., Cañuelo, A., Sánchez, A., Clarke, D. J., Marchal, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638862/
https://www.ncbi.nlm.nih.gov/pubmed/29026105
http://dx.doi.org/10.1038/s41598-017-12793-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638862/
https://www.ncbi.nlm.nih.gov/pubmed/29026105
http://dx.doi.org/10.1038/s41598-017-12793-7

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