Translesion synthesis DNA polymerase η exhibits a specific RNA extension activity and a transcription-associated function

Polymerase eta (Polη) is a low fidelity translesion synthesis DNA polymerase that rescues damage-stalled replication by inserting deoxy-ribonucleotides opposite DNA damage sites resulting in error-free or mutagenic damage bypass. In this study we identify a new specific RNA extension activity of Pol...

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Detalles Bibliográficos
Autores principales: Gali, Vamsi K., Balint, Eva, Serbyn, Nataliia, Frittmann, Orsolya, Stutz, Francoise, Unk, Ildiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638924/
https://www.ncbi.nlm.nih.gov/pubmed/29026143
http://dx.doi.org/10.1038/s41598-017-12915-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638924/
https://www.ncbi.nlm.nih.gov/pubmed/29026143
http://dx.doi.org/10.1038/s41598-017-12915-1

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