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Combined skin and muscle vaccination differentially impact the quality of effector T cell functions: the CUTHIVAC-001 randomized trial

Targeting of different tissues via transcutaneous (TC), intradermal (ID) and intramuscular (IM) injection has the potential to tailor the immune response to DNA vaccination. In this Phase I randomised controlled clinical trial in HIV-1 negative volunteers we investigate whether the site and mode of...

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Detalles Bibliográficos
Autores principales: Haidari, G., Cope, A., Miller, A., Venables, S., Yan, C., Ridgers, H., Reijonen, K., Hannaman, D., Spentzou, A., Hayes, P., Bouliotis, G., Vogt, A., Joseph, S., Combadiere, B., McCormack, S., Shattock, R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638927/
https://www.ncbi.nlm.nih.gov/pubmed/29026141
http://dx.doi.org/10.1038/s41598-017-13331-1