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Genetic and Epigenetic Profiling Reveals EZH2-mediated Down Regulation of OCT-4 Involves NR2F2 during Cardiac Differentiation of Human Embryonic Stem Cells

Human embryonic (hES) stem cells are widely used as an in vitro model to understand global genetic and epigenetic changes that occur during early embryonic development. In-house derived hES cells (KIND1) were subjected to directed differentiation into cardiovascular progenitors (D12) and beating car...

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Detalles Bibliográficos
Autores principales: Pursani, Varsha, Pethe, Prasad, Bashir, Mohsin, Sampath, Prabha, Tanavde, Vivek, Bhartiya, Deepa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638931/
https://www.ncbi.nlm.nih.gov/pubmed/29026152
http://dx.doi.org/10.1038/s41598-017-13442-9