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Mechanical stress induces elastic fibre disruption and cartilage matrix increase in ligamentum flavum

Lumbar spinal stenosis (LSS) is one of the most frequent causes of low back pain and gait disturbance in the elderly. Ligamentum flavum (LF) hypertrophy is the main pathomechanism of LSS, but the reason for its occurrence is not clearly elucidated. In this study, we established a novel animal model...

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Detalles Bibliográficos
Autores principales: Hayashi, Kazunori, Suzuki, Akinobu, Abdullah Ahmadi, Sayed, Terai, Hidetomi, Yamada, Kentaro, Hoshino, Masatoshi, Toyoda, Hiromitsu, Takahashi, Shinji, Tamai, Koji, Ohyama, Shoichiro, Javid, Akgar, Suhrab Rahmani, Mohammad, Hasib, Maruf Mohammad, Nakamura, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638934/
https://www.ncbi.nlm.nih.gov/pubmed/29026131
http://dx.doi.org/10.1038/s41598-017-13360-w