Production and evaluation of parathyroid hormone receptor(1) ligands with intrinsic or assembled peroxidase domains

Parathyroid hormone (PTH) can be C-terminally extended without significant affinity loss for the PTH(1) receptor (PTHR(1)). We developed fusion protein ligands with enzymatic activity to probe PTHR(1)s at the cell surface. Two fusion proteins were generated by linking PTH to the N-terminus of either...

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Detalles Bibliográficos
Autores principales: Charest-Morin, Xavier, Poubelle, Patrice E., Marceau, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638942/
https://www.ncbi.nlm.nih.gov/pubmed/29026164
http://dx.doi.org/10.1038/s41598-017-13548-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638942/
https://www.ncbi.nlm.nih.gov/pubmed/29026164
http://dx.doi.org/10.1038/s41598-017-13548-0

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