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Nanoparticulate vacuolar ATPase blocker exhibits potent host-targeted antiviral activity against feline coronavirus

Feline infectious peritonitis (FIP), caused by a mutated feline coronavirus, is one of the most serious and fatal viral diseases in cats. The disease remains incurable, and there is no effective vaccine available. In light of the pathogenic mechanism of feline coronavirus that relies on endosomal ac...

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Detalles Bibliográficos
Autores principales: Hu, Che-Ming Jack, Chang, Wei-Shan, Fang, Zih-Syun, Chen, You-Ting, Wang, Wen-Lin, Tsai, Hsiao-Han, Chueh, Ling-Ling, Takano, Tomomi, Hohdatsu, Tsutomu, Chen, Hui-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638965/
https://www.ncbi.nlm.nih.gov/pubmed/29026122
http://dx.doi.org/10.1038/s41598-017-13316-0