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Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles

Muscle stem cells (MuSCs) contribute to muscle regeneration following injury. In many muscle disorders, the repeated cycles of damage and repair lead to stem cell dysfunction. While telomere attrition may contribute to aberrant stem cell functions, methods to accurately measure telomere length in st...

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Detalles Bibliográficos
Autores principales: Tichy, Elisia D., Sidibe, David K., Tierney, Matthew T., Stec, Michael J., Sharifi-Sanjani, Maryam, Hosalkar, Harish, Mubarak, Scott, Johnson, F. Brad, Sacco, Alessandra, Mourkioti, Foteini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639167/
https://www.ncbi.nlm.nih.gov/pubmed/28890163
http://dx.doi.org/10.1016/j.stemcr.2017.08.003