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Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation

Kidney ischemia and reperfusion injury (IRI) is associated with a high mortality rate, which is attributed to tubular oxidative and nitrative stresses; however, an effective approach to limit IRI remains elusive. Spermidine, a naturally occurring polyamine, protects yeast cells against aging through...

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Detalles Bibliográficos
Autor principal: Kim, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Anatomists 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639174/
https://www.ncbi.nlm.nih.gov/pubmed/29043098
http://dx.doi.org/10.5115/acb.2017.50.3.200