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PDGFRA Is Not Essential for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines

Extraembryonic endoderm stem (XEN) cell lines can be derived and maintained in vitro and reflect the primitive endoderm lineage. Platelet-derived growth factor receptor alpha (PDGFRA) is thought to be essential for the derivation and maintenance of mouse XEN cell lines. Here, we have re-evaluated th...

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Detalles Bibliográficos
Autores principales: Lin, Jiangwei, Khan, Mona, Zapiec, Bolek, Mombaerts, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639183/
https://www.ncbi.nlm.nih.gov/pubmed/28919262
http://dx.doi.org/10.1016/j.stemcr.2017.08.005