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Prolactin Alters the Mammary Epithelial Hierarchy, Increasing Progenitors and Facilitating Ovarian Steroid Action

Hormones drive mammary development and function and play critical roles in breast cancer. Epidemiologic studies link prolactin (PRL) to increased risk for aggressive cancers that express estrogen receptor α (ERα). However, in contrast to ovarian steroids, PRL actions on the mammary gland outside of...

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Detalles Bibliográficos
Autores principales: O'Leary, Kathleen A., Shea, Michael P., Salituro, Stephanie, Blohm, Courtney E., Schuler, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639259/
https://www.ncbi.nlm.nih.gov/pubmed/28919264
http://dx.doi.org/10.1016/j.stemcr.2017.08.011