Single-Cell Gene Expression Analysis of a Human ESC Model of Pancreatic Endocrine Development Reveals Different Paths to β-Cell Differentiation

The production of insulin-producing β cells from human embryonic stem cells (hESCs) in vitro represents a promising strategy for a cell-based therapy for type 1 diabetes mellitus. To explore the cellular heterogeneity and temporal progression of endocrine progenitors and their progeny, we performed...

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Detalles Bibliográficos
Autores principales: Petersen, Maja Borup Kjær, Azad, Ajuna, Ingvorsen, Camilla, Hess, Katja, Hansson, Mattias, Grapin-Botton, Anne, Honoré, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639261/
https://www.ncbi.nlm.nih.gov/pubmed/28919263
http://dx.doi.org/10.1016/j.stemcr.2017.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639261/
https://www.ncbi.nlm.nih.gov/pubmed/28919263
http://dx.doi.org/10.1016/j.stemcr.2017.08.009

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