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Keratin-14-Positive Precursor Cells Spawn a Population of Migratory Corneal Epithelia that Maintain Tissue Mass throughout Life

The dynamics of epithelial stem cells (SCs) that contribute to the formation and maintenance of the cornea are poorly understood. Here, we used K14CreER(T2)-Confetti (Confetti) mice, sophisticated imaging, and computational modeling to trace the origins and fate of these cells during embryogenesis a...

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Detalles Bibliográficos
Autores principales: Richardson, Alexander, Lobo, Erwin P., Delic, Naomi C., Myerscough, Mary R., Lyons, J. Guy, Wakefield, Denis, Di Girolamo, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639292/
https://www.ncbi.nlm.nih.gov/pubmed/28943255
http://dx.doi.org/10.1016/j.stemcr.2017.08.015