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Intramyocardial delivery of bFGF with a biodegradable and thermosensitive hydrogel improves angiogenesis and cardio-protection in infarcted myocardium

Basic fibroblast growth factor (bFGF), a known angiogenic factor, may provide a potential strategy for the treatment of myocardial infarction (MI), but it is limited by a relatively short half-life. Dex-PCL-HEMA/PNIPAAm hydrogel provides a reservoir for the controlled release of growth factors. The...

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Detalles Bibliográficos
Autores principales: Zhu, Hongling, Li, Xiaoyan, Yuan, Mingjie, Wan, Weiguo, Hu, Miaoyang, Wang, Xiaoding, Jiang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639332/
https://www.ncbi.nlm.nih.gov/pubmed/29042955
http://dx.doi.org/10.3892/etm.2017.5015