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ERβ compensates for the absence of ERα function to promote osteoblast viability by inhibition of SOST signaling

Estrogen receptors α and β (ERα and ERβ) serve key functions in bone development and maintenance, and in the metabolism of bone mineral. ERβ and ERα form heterodimers, and ERβ negatively regulates the transactivation of ERα. ERβ also inhibits recruitment of ERα to the estrogen-responsive promoters....

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Detalles Bibliográficos
Autores principales: Lu, Shijin, Sun, Changying, Miao, Congxiu, Zhao, Zhongfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639354/
https://www.ncbi.nlm.nih.gov/pubmed/29042923
http://dx.doi.org/10.3892/etm.2017.5014