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ERβ compensates for the absence of ERα function to promote osteoblast viability by inhibition of SOST signaling
Estrogen receptors α and β (ERα and ERβ) serve key functions in bone development and maintenance, and in the metabolism of bone mineral. ERβ and ERα form heterodimers, and ERβ negatively regulates the transactivation of ERα. ERβ also inhibits recruitment of ERα to the estrogen-responsive promoters....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639354/ https://www.ncbi.nlm.nih.gov/pubmed/29042923 http://dx.doi.org/10.3892/etm.2017.5014 |