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An RNAi Screen Reveals an Essential Role for HIPK4 in Human Skin Epithelial Differentiation from iPSCs

Molecular mechanisms responsible for the development of human skin epithelial cells are incompletely understood. As a consequence, the efficiency to establish a pure skin epithelial cell population from human induced pluripotent stem cells (hiPSCs) remains poor. Using an approach including RNAi and...

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Detalles Bibliográficos
Autores principales: Larribère, Lionel, Galach, Marta, Novak, Daniel, Arévalo, Karla, Volz, Hans Christian, Stark, Hans-Jürgen, Boukamp, Petra, Boutros, Michael, Utikal, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639458/
https://www.ncbi.nlm.nih.gov/pubmed/28966120
http://dx.doi.org/10.1016/j.stemcr.2017.08.023