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Impaired T-cell migration to the CNS under fingolimod and dimethyl fumarate

OBJECTIVE: To evaluate the long-term effects of treatments used in MS on the T-cell trafficking profile. METHODS: We enrolled 83 patients with MS under fingolimod (FTY), natalizumab (NTZ), dimethyl fumarate (DMF), or other disease-modifying treatments (DMTs). Blood was drawn before treatment onset a...

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Detalles Bibliográficos
Autores principales: Mathias, Amandine, Perriot, Sylvain, Canales, Mathieu, Blatti, Claudia, Gaubicher, Coline, Schluep, Myriam, Engelhardt, Britta, Du Pasquier, Renaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639463/
https://www.ncbi.nlm.nih.gov/pubmed/29075657
http://dx.doi.org/10.1212/NXI.0000000000000401