A Scaled Framework for CRISPR Editing of Human Pluripotent Stem Cells to Study Psychiatric Disease

Scaling of CRISPR-Cas9 technology in human pluripotent stem cells (hPSCs) represents an important step for modeling complex disease and developing drug screens in human cells. However, variables affecting the scaling efficiency of gene editing in hPSCs remain poorly understood. Here, we report a sta...

Descripción completa

Detalles Bibliográficos
Autores principales: Hazelbaker, Dane Z., Beccard, Amanda, Bara, Anne M., Dabkowski, Nicole, Messana, Angelica, Mazzucato, Patrizia, Lam, Daisy, Manning, Danielle, Eggan, Kevin, Barrett, Lindy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639480/
https://www.ncbi.nlm.nih.gov/pubmed/29020615
http://dx.doi.org/10.1016/j.stemcr.2017.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639480/
https://www.ncbi.nlm.nih.gov/pubmed/29020615
http://dx.doi.org/10.1016/j.stemcr.2017.09.006

Ejemplares similares