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Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension

BACKGROUND: Meaningful translational large animal models for cardiac diseases are indispensable for studying disease mechanisms, development of novel therapeutic strategies, and evaluation of potential drugs. METHODS: For induction of heart failure, cardiac hypertrophy and fibrosis, a bare metal ste...

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Detalles Bibliográficos
Autores principales: Gyöngyösi, Mariann, Pavo, Noemi, Lukovic, Dominika, Zlabinger, Katrin, Spannbauer, Andreas, Traxler, Denise, Goliasch, Georg, Mandic, Ljubica, Bergler-Klein, Jutta, Gugerell, Alfred, Jakab, Andras, Szankai, Zsuzsanna, Toth, Levente, Garamvölgyi, Rita, Maurer, Gerald, Jaisser, Frederic, Zannad, Faiez, Thum, Thomas, Bátkai, Sándor, Winkler, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639584/
https://www.ncbi.nlm.nih.gov/pubmed/28985746
http://dx.doi.org/10.1186/s12967-017-1299-0

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