Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension
BACKGROUND: Meaningful translational large animal models for cardiac diseases are indispensable for studying disease mechanisms, development of novel therapeutic strategies, and evaluation of potential drugs. METHODS: For induction of heart failure, cardiac hypertrophy and fibrosis, a bare metal ste...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639584/ https://www.ncbi.nlm.nih.gov/pubmed/28985746 http://dx.doi.org/10.1186/s12967-017-1299-0 |