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An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia

BACKGROUND: Xenotransplantation of patient-derived AML (acute myeloid leukemia) cells in NOD-scid Il2rγ (null) (NSG) mice is the method of choice for evaluating this human hematologic malignancy. However, existing models constructed using intravenous injection in adult or newborn NSG mice have infer...

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Detalles Bibliográficos
Autores principales: Her, Zhisheng, Yong, Kylie Su Mei, Paramasivam, Kathirvel, Tan, Wilson Wei Sheng, Chan, Xue Ying, Tan, Sue Yee, Liu, Min, Fan, Yong, Linn, Yeh Ching, Hui, Kam Man, Surana, Uttam, Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639594/
https://www.ncbi.nlm.nih.gov/pubmed/28985760
http://dx.doi.org/10.1186/s13045-017-0532-x