Cargando…
An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia
BACKGROUND: Xenotransplantation of patient-derived AML (acute myeloid leukemia) cells in NOD-scid Il2rγ (null) (NSG) mice is the method of choice for evaluating this human hematologic malignancy. However, existing models constructed using intravenous injection in adult or newborn NSG mice have infer...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639594/ https://www.ncbi.nlm.nih.gov/pubmed/28985760 http://dx.doi.org/10.1186/s13045-017-0532-x |