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Role of microglial amylin receptors in mediating beta amyloid (Aβ)-induced inflammation

BACKGROUND: Neuroinflammation in the brain consequent to activation of microglia is viewed as an important component of Alzheimer’s disease (AD) pathology. Amyloid beta (Aβ) protein is known to activate microglia and unleash an inflammatory cascade that eventually results in neuronal dysfunction and...

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Detalles Bibliográficos
Autores principales: Fu, Wen, Vukojevic, Vlatka, Patel, Aarti, Soudy, Rania, MacTavish, David, Westaway, David, Kaur, Kamaljit, Goncharuk, Valeri, Jhamandas, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639602/
https://www.ncbi.nlm.nih.gov/pubmed/28985759
http://dx.doi.org/10.1186/s12974-017-0972-9