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Role of microglial amylin receptors in mediating beta amyloid (Aβ)-induced inflammation
BACKGROUND: Neuroinflammation in the brain consequent to activation of microglia is viewed as an important component of Alzheimer’s disease (AD) pathology. Amyloid beta (Aβ) protein is known to activate microglia and unleash an inflammatory cascade that eventually results in neuronal dysfunction and...
Autores principales: | Fu, Wen, Vukojevic, Vlatka, Patel, Aarti, Soudy, Rania, MacTavish, David, Westaway, David, Kaur, Kamaljit, Goncharuk, Valeri, Jhamandas, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639602/ https://www.ncbi.nlm.nih.gov/pubmed/28985759 http://dx.doi.org/10.1186/s12974-017-0972-9 |
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