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Spatial sequestration and oligomer remodeling during de novo [PSI(+)] formation

Prions are misfolded, aggregated, infectious proteins found in a range of organisms from mammals to bacteria. In mammals, prion formation is difficult to study because misfolding and aggregation take place prior to symptom presentation. The study of the yeast prion [PSI(+)], which is the misfolded i...

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Detalles Bibliográficos
Autores principales: Lyke, Douglas R., Manogaran, Anita L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639836/
https://www.ncbi.nlm.nih.gov/pubmed/28968144
http://dx.doi.org/10.1080/19336896.2017.1368606