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A novel immunotoxin reveals a new role for CD321 in endothelial cells

There are currently several antibody therapies that directly target tumors, and antibody-drug conjugates represent a novel moiety as next generation therapeutics. Here, we used a unique screening probe, DT3C, to identify functional antibodies that recognized surface molecules and functional epitopes...

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Detalles Bibliográficos
Autores principales: Fukuhara, Takeshi, Kim, Jia, Hokaiwado, Shintaro, Nawa, Makiko, Okamoto, Hayato, Kogiso, Tomohiko, Watabe, Tetsuro, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640210/
https://www.ncbi.nlm.nih.gov/pubmed/29028806
http://dx.doi.org/10.1371/journal.pone.0181502