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The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent

Multiple myeloma (MM), a malignancy of the bone marrow, is characterized by a pathological increase in antibody-producing plasma cells and an increase in immunoglobulins (plasmacytosis). In recent years, bone morphogenetic proteins (BMPs) have been reported to be activators of apoptotic cell death i...

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Detalles Bibliográficos
Autores principales: Lagler, Charlotte, El-Mesery, Mohamed, Kübler, Alexander Christian, Müller-Richter, Urs Dietmar Achim, Stühmer, Thorsten, Nickel, Joachim, Müller, Thomas Dieter, Wajant, Harald, Seher, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640214/
https://www.ncbi.nlm.nih.gov/pubmed/29028819
http://dx.doi.org/10.1371/journal.pone.0185720