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Short-term vitamin E treatment impairs reactive oxygen species signaling required for adipose tissue expansion, resulting in fatty liver and insulin resistance in obese mice

OBJECTIVES: The use of antioxidant therapy in the treatment of oxidative stress-related diseases such as cardiovascular disease, diabetes or obesity remains controversial. Our aim is to demonstrate that antioxidant supplementation may promote negative effects if used before the establishment of oxid...

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Detalles Bibliográficos
Autores principales: Alcala, Martin, Calderon-Dominguez, Maria, Serra, Dolors, Herrero, Laura, Ramos, Maria P., Viana, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640231/
https://www.ncbi.nlm.nih.gov/pubmed/29028831
http://dx.doi.org/10.1371/journal.pone.0186579