Nasal DNA methylation differentiates corticosteroid treatment response in pediatric asthma: A pilot study

BACKGROUND: Treatment response to systemic corticosteroid in asthmatic children is heterogeneous and may be mediated by epigenetic mechanism(s). We aim to identify DNA methylation (DNAm) changes responsive to steroid, and DNAm biomarkers that distinguish treatment response. MATERIALS AND METHODS: We...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Biagini Myers, Jocelyn M., Yadagiri, Veda K., Ulm, Ashley, Chen, Xiaoting, Weirauch, Matthew T., Khurana Hershey, Gurjit K., Ji, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640236/
https://www.ncbi.nlm.nih.gov/pubmed/29028809
http://dx.doi.org/10.1371/journal.pone.0186150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640236/
https://www.ncbi.nlm.nih.gov/pubmed/29028809
http://dx.doi.org/10.1371/journal.pone.0186150

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