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Interleukin-1 receptor antagonist inhibits angiogenesis via blockage IL-1α/PI3K/NF-κβ pathway in human colon cancer cell

PURPOSE: This article investigates the relationship between cancer cells and stromal cells in carcinoma cell living microenvironment and elucidates the mechanism that interleukin-1 receptor antagonist (IL-1RA) blocks metastatic potential in colon cancer. METHODS: Western blot and RT-PCR assay were u...

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Detalles Bibliográficos
Autores principales: Ma, Jiachi, Sun, Xiaowen, Guo, Tiankang, Su, He, Chen, Quan, Gong, Zhenqiang, Qi, Jianbo, Zhao, Xiaodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640395/
https://www.ncbi.nlm.nih.gov/pubmed/29062241
http://dx.doi.org/10.2147/CMAR.S147699