Cargando…

Interleukin-1 receptor antagonist inhibits angiogenesis via blockage IL-1α/PI3K/NF-κβ pathway in human colon cancer cell

PURPOSE: This article investigates the relationship between cancer cells and stromal cells in carcinoma cell living microenvironment and elucidates the mechanism that interleukin-1 receptor antagonist (IL-1RA) blocks metastatic potential in colon cancer. METHODS: Western blot and RT-PCR assay were u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Jiachi, Sun, Xiaowen, Guo, Tiankang, Su, He, Chen, Quan, Gong, Zhenqiang, Qi, Jianbo, Zhao, Xiaodan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640395/ https://www.ncbi.nlm.nih.gov/pubmed/29062241 http://dx.doi.org/10.2147/CMAR.S147699

Ejemplares similares

Interleukin-1 receptor antagonist inhibits angiogenesis in gastric cancer
por: Gong, Zhenqiang, et al.
Publicado: (2018)

Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion
por: Marazioti, Antonia, et al.
Publicado: (2018)

Investigation of Leoligin Derivatives as NF-κΒ Inhibitory Agents
por: Linder, Thomas, et al.
Publicado: (2021)

NF-κβ: A Potential Target in the Management of Vascular Complications of Diabetes
por: Suryavanshi, Sachin V., et al.
Publicado: (2017)

1-Methyl-D-tryptophan Reduces Tumor CD133(+) cells, Wnt/β-catenin and NF-κβp65 while Enhances Lymphocytes NF-κβ2, STAT3, and STAT4 Pathways in Murine Pancreatic Adenocarcinoma
por: Alahdal, Murad, et al.
Publicado: (2018)

The Role of Mesenchymal Stem Cells with Ascorbic Acid and N-Acetylcysteine on TNF-α, IL 1β, and NF-κβ Expressions in Acute Pancreatitis in Albino Rats
por: Abdelhafez, Dalia, et al.
Publicado: (2021)

Blockage of interleukin-1β with canakinumab in patients with Covid-19
por: Landi, Lorenza, et al.
Publicado: (2020)

3D micro-environment regulates NF-κβ dependent adhesion to induce monocyte differentiation
por: Bhattacharya, Anindita, et al.
Publicado: (2018)

Differential expression in genes involved in the NF-κβ pathway among asymptomatic HTLV-1 carriers and HAM/TSP patients in Peru
por: Talledo, Michael, et al.
Publicado: (2014)

Aurora-B Promotes Osteosarcoma Cell Growth and Metastasis Through Activation of the NPM1/ERK/NF-κβ/MMPs Axis
por: Song, Honghai, et al.
Publicado: (2020)

Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathway
por: Arenas, Yaiza M., et al.
Publicado: (2020)

Clozapine-induced cardiotoxicity in rats: Involvement of tumour necrosis factor alpha, NF-κβ and caspase-3
por: Abdel-Wahab, Basel A., et al.
Publicado: (2014)

MDM2 inhibitor ameliorates cisplatin‐induced nephropathy via NFκΒ signal inhibition
por: Fujikura, Tomoyuki, et al.
Publicado: (2018)

Ambrosin, a potent NF-κβ inhibitor, ameliorates lipopolysaccharide induced memory impairment, comparison to curcumin
por: Khalil, Mohammed N. A., et al.
Publicado: (2019)

Influence of Polymorphism in the Genes for the Interleukin (IL)-1 Receptor Antagonist and IL-1β on Tuberculosis
por: Wilkinson, Robert J., et al.
Publicado: (1999)

CDK7 inhibition suppresses rheumatoid arthritis inflammation via blockage of NF‐κB activation and IL‐1β/IL‐6 secretion
por: Hong, Honghai, et al.
Publicado: (2017)

Production of interleukin (IL)-1 receptor antagonist by human articular chondrocytes
por: Palmer, G, et al.
Publicado: (2002)

Kanglaite inhibits EMT caused by TNF-α via NF-κΒ inhibition in colorectal cancer cells
por: Shi, Guiling, et al.
Publicado: (2017)

Kanglaite sensitizes colorectal cancer cells to Taxol via NF-κΒ inhibition and connexin 43 upregulation
por: Wang, Yijia, et al.
Publicado: (2017)

Zerumbone Suppresses Enterotoxigenic Bacteroides fragilis Infection-Induced Colonic Inflammation through Inhibition of NF-κΒ
por: Hwang, Soonjae, et al.
Publicado: (2019)

Chrysin ameliorates STZ-induced diabetes in rats: possible impact of modulation of TLR4/NF-κβ pathway
por: Salama, Abeer, et al.
Publicado: (2021)

Human amniotic membrane modulates Wnt/β-catenin and NF-κβ signaling pathways in articular chondrocytes in vitro
por: Chung, Connie, et al.
Publicado: (2021)

Curcumin Mitigates Malathion-Induced Renal Injury: Suppression of Apoptosis and Modulation of NF-κβ/TNF-α and Nrf2, and HO-1 Signaling
por: Eldesoqui, Mamdouh, et al.
Publicado: (2023)

Interleukin-1B (IL-1B-31 and IL-1B-511) and interleukin-1 receptor antagonist (IL-1Ra) gene polymorphisms in primary immune thrombocytopenia
por: Yadav, Deependra Kumar, et al.
Publicado: (2017)

Regulation of Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κβ) in Inflammatory Bowel Diseases
por: Zaidi, Deenaz, et al.
Publicado: (2018)

Altered Adhesion and Migration of Human Mesenchymal Stromal Cells under Febrile Temperature Stress Involves NF-κβ Pathway
por: Sen, Ankita, et al.
Publicado: (2020)

Orlistat Mitigates Oxidative Stress-Linked Myocardial Damage via NF-κβ- and Caspase-Dependent Activities in Obese Rats
por: Othman, Zaidatul Akmal, et al.
Publicado: (2022)

Rosemarinic acid protects β-cell from STZ-induced cell damage via modulating NF-κβ pathway
por: El-Huneidi, Waseem, et al.
Publicado: (2023)

Meclizine moderates lipopolysaccharide-induced neuroinflammation in mice through the regulation of AKT/ NF-κβ/ERK/JNK signaling pathway
por: Mostafa, Rasha E., et al.
Publicado: (2023)

The effect of an interleukin receptor antagonist (IL-1ra) on colonocyte eicosanoid release
por: Smith, G. S., et al.
Publicado: (1996)

Enhanced Angiogenesis by 11βHSD1 Blockage Is Insufficient to Improve Reperfusion Following Hindlimb Ischaemia
por: Wu, Junxi, et al.
Publicado: (2022)

Author Correction: Kanglaite sensitizes colorectal cancer cells to Taxol via NF-κΒ inhibition and connexin 43 upregulation
por: Wang, Yijia, et al.
Publicado: (2018)

Cardamonin Exerts Antitumor Effect on Human Hepatocellular Carcinoma Xenografts in Athymic Nude Mice through Inhibiting NF-κβ Pathway
por: Badroon, Nassrin, et al.
Publicado: (2020)

Gastroprotective effects of diosgenin against HCl/ethanol-induced gastric mucosal injury through suppression of NF-κβ and myeloperoxidase activities
por: Zhao, Hengfang, et al.
Publicado: (2021)

RID: Evaluation of the Possible Inhibiting Effect of the Proinflammatory Signaling Induced by TNF-α through NF-κβ and AP-1 in Two Cell Lines of Breast Cancer
por: Monsalve, F. A., et al.
Publicado: (2020)

Effects of leflunomide on interleukin-1 receptor antagonist (IL-1Ra) synthesis in chondrocytes and synovial fibroblasts
por: Palmer, G, et al.
Publicado: (2003)

The Experimental Treatment of Corneal Graft Rejection with the Interleukin-1 Receptor Antagonist (IL-1ra) Gene
por: Yuan, Jin, et al.
Publicado: (2013)

Breast cancer pathogenesis is linked to the intra-tumoral estrogen sulfotransferase (hSULT1E1) expressions regulated by cellular redox dependent Nrf-2/NFκβ interplay
por: Nazmeen, Aarifa, et al.
Publicado: (2020)

Hypoxia Induces Pro-Fibrotic and Fibrosis Marker Genes in Hepatocellular Carcinoma Cells Independently of Inflammatory Stimulation and the NF-κΒ Pathway
por: Triantafyllou, Eleni-Anastasia, et al.
Publicado: (2019)

Protective Effects of Bisoprolol Against Cadmium-induced Myocardial Toxicity Through Inhibition of Oxidative Stress and NF-κΒ Signalling in Rats
por: Liu, Jinhua, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9plebirj6r938m6ad21a3nsllg