Optimization and physicochemical characterization of a cationic lipid-phosphatidylcholine mixed emulsion formulated as a highly efficient vehicle that facilitates adenoviral gene transfer

Cationic lipid-based nanoparticles enhance viral gene transfer by forming electrostatic complexes with adenoviral vectors. We recently demonstrated the superior complexation capabilities of 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) emulsion compared with a liposomal counterpart but the cytoto...

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Detalles Bibliográficos
Autores principales: Kim, Soo-Yeon, Lee, Sang-Jin, Kim, Jin-Ki, Choi, Han-Gon, Lim, Soo-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640419/
https://www.ncbi.nlm.nih.gov/pubmed/29070949
http://dx.doi.org/10.2147/IJN.S146785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640419/
https://www.ncbi.nlm.nih.gov/pubmed/29070949
http://dx.doi.org/10.2147/IJN.S146785

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