Cargando…

CCDC88B is required for pathogenesis of inflammatory bowel disease

Inflammatory bowel disease (IBD) involves interaction between host genetic factors and environmental triggers. CCDC88B maps within one IBD risk locus on human chromosome 11q13. Here we show that CCDC88B protein increases in the colon during intestinal injury, concomitant with an influx of CCDC88B(+)...

Descripción completa

Detalles Bibliográficos
Autores principales: Fodil, Nassima, Moradin, Neda, Leung, Vicki, Olivier, Jean-Frederic, Radovanovic, Irena, Jeyakumar, Thiviya, Flores Molina, Manuel, McFarquhar, Ashley, Cayrol, Romain, Bozec, Dominique, Shoukry, Naglaa H., Kubo, Michiaki, Dimitrieva, Julia, Louis, Edouard, Theatre, Emilie, Dahan, Stephanie, Momozawa, Yukihide, Georges, Michel, Yeretssian, Garabet, Gros, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640600/
https://www.ncbi.nlm.nih.gov/pubmed/29030607
http://dx.doi.org/10.1038/s41467-017-01381-y