Cargando…
CCDC88B is required for pathogenesis of inflammatory bowel disease
Inflammatory bowel disease (IBD) involves interaction between host genetic factors and environmental triggers. CCDC88B maps within one IBD risk locus on human chromosome 11q13. Here we show that CCDC88B protein increases in the colon during intestinal injury, concomitant with an influx of CCDC88B(+)...
Autores principales: | Fodil, Nassima, Moradin, Neda, Leung, Vicki, Olivier, Jean-Frederic, Radovanovic, Irena, Jeyakumar, Thiviya, Flores Molina, Manuel, McFarquhar, Ashley, Cayrol, Romain, Bozec, Dominique, Shoukry, Naglaa H., Kubo, Michiaki, Dimitrieva, Julia, Louis, Edouard, Theatre, Emilie, Dahan, Stephanie, Momozawa, Yukihide, Georges, Michel, Yeretssian, Garabet, Gros, Philippe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640600/ https://www.ncbi.nlm.nih.gov/pubmed/29030607 http://dx.doi.org/10.1038/s41467-017-01381-y |
Ejemplares similares
-
Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer
por: Jeyakumar, Thiviya, et al.
Publicado: (2019) -
CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation
por: Kennedy, James M., et al.
Publicado: (2014) -
Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis
por: Bozec, Dominique, et al.
Publicado: (2016) -
Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma
por: Dunkin, David, et al.
Publicado: (2018) -
NOD-Like Receptors in Intestinal Homeostasis and Epithelial Tissue Repair
por: Parlato, Marianna, et al.
Publicado: (2014)