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Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo
Establishment of cell polarity in the mammalian embryo is fundamental for the first cell fate decision that sets aside progenitor cells for both the new organism and the placenta. Yet the sequence of events and molecular mechanism that trigger this process remain unknown. Here, we show that de novo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640629/ https://www.ncbi.nlm.nih.gov/pubmed/29030553 http://dx.doi.org/10.1038/s41467-017-00977-8 |