HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions

The vitamin D receptor/retinoid X receptor-α heterodimer (VDRRXRα) regulates bone mineralization via transcriptional control of osteocalcin (BGLAP) gene and is the receptor for 1α,25-dihydroxyvitamin D(3) (1,25D3). However, supra-physiological levels of 1,25D3 activates the calcium-regulating gene T...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Jie, Chang, Mi Ra, Stites, Ryan E., Wang, Yong, Bruning, John B., Pascal, Bruce D., Novick, Scott J., Garcia-Ordonez, Ruben D., Stayrook, Keith R., Chalmers, Michael J., Dodge, Jeffrey A., Griffin, Patrick R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640644/
https://www.ncbi.nlm.nih.gov/pubmed/29030554
http://dx.doi.org/10.1038/s41467-017-00978-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640644/
https://www.ncbi.nlm.nih.gov/pubmed/29030554
http://dx.doi.org/10.1038/s41467-017-00978-7

Ejemplares similares