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BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells
Toll-like receptors (TLR) are essential components of the innate immune system. Several accessory proteins, such as UNC93B1, are required for transport and activation of nucleic acid sensing Toll-like receptors in endosomes. Here, we show that BAD-LAMP (LAMP5) controls TLR9 trafficking to LAMP1(+) l...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640662/ https://www.ncbi.nlm.nih.gov/pubmed/29030552 http://dx.doi.org/10.1038/s41467-017-00695-1 |