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Active GSK3β and an intact β-catenin TCF complex are essential for the differentiation of human myogenic progenitor cells

Wnt-β-catenin signalling is essential for skeletal muscle myogenesis during development, but its role in adult human skeletal muscle remains unknown. Here we have used human primary CD56(Pos) satellite cell-derived myogenic progenitors obtained from healthy individuals to study the role of Wnt-β-cat...

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Detalles Bibliográficos
Autores principales: Agley, C. C., Lewis, F. C., Jaka, O., Lazarus, N. R., Velloso, C., Francis-West, P., Ellison-Hughes, G. M., Harridge, S. D. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640663/
https://www.ncbi.nlm.nih.gov/pubmed/29030569
http://dx.doi.org/10.1038/s41598-017-10731-1