Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

At the stage of carcinoma in situ, the basement membrane (BM) segregates tumor cells from the stroma. This barrier must be breached to allow dissemination of the tumor cells to adjacent tissues. Cancer cells can perforate the BM using proteolysis; however, whether stromal cells play a role in this p...

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Detalles Bibliográficos
Autores principales: Glentis, Alexandros, Oertle, Philipp, Mariani, Pascale, Chikina, Aleksandra, El Marjou, Fatima, Attieh, Youmna, Zaccarini, Francois, Lae, Marick, Loew, Damarys, Dingli, Florent, Sirven, Philemon, Schoumacher, Marie, Gurchenkov, Basile G., Plodinec, Marija, Vignjevic, Danijela Matic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640679/
https://www.ncbi.nlm.nih.gov/pubmed/29030636
http://dx.doi.org/10.1038/s41467-017-00985-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640679/
https://www.ncbi.nlm.nih.gov/pubmed/29030636
http://dx.doi.org/10.1038/s41467-017-00985-8

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