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Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns

The increased number of annotated bacterial genomes provides a vast resource for genome mining. Several bacterial natural products with epoxide groups have been identified as pre-mRNA spliceosome inhibitors and antitumor compounds through genome mining. These epoxide-containing natural products feat...

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Detalles Bibliográficos
Autor principal: Liu, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640691/
https://www.ncbi.nlm.nih.gov/pubmed/29062932
http://dx.doi.org/10.1016/j.synbio.2016.01.007