Cargando…
Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns
The increased number of annotated bacterial genomes provides a vast resource for genome mining. Several bacterial natural products with epoxide groups have been identified as pre-mRNA spliceosome inhibitors and antitumor compounds through genome mining. These epoxide-containing natural products feat...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640691/ https://www.ncbi.nlm.nih.gov/pubmed/29062932 http://dx.doi.org/10.1016/j.synbio.2016.01.007 |