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CRISPy-web: An online resource to design sgRNAs for CRISPR applications

CRISPR/Cas9-based genome editing has been one of the major achievements of molecular biology, allowing the targeted engineering of a wide range of genomes. The system originally evolved in prokaryotes as an adaptive immune system against bacteriophage infections. It now sees widespread application i...

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Detalles Bibliográficos
Autores principales: Blin, Kai, Pedersen, Lasse Ebdrup, Weber, Tilmann, Lee, Sang Yup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640694/
https://www.ncbi.nlm.nih.gov/pubmed/29062934
http://dx.doi.org/10.1016/j.synbio.2016.01.003