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Activation of NF-kB-Mediated TNF-Induced Antimicrobial Immunity Is Required for the Efficient Brucella abortus Clearance in RAW 264.7 Cells

In this study, we explore the regulatory roles of pro-inflammatory cytokine tumor necrosis factor alpha (TNF) in the innate immunity of macrophages against B. abortus infection. We show that infection of macrophage with B. abortus induces marked expression and secretion of TNF which subsequently bin...

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Detalles Bibliográficos
Autores principales: Hop, Huynh T., Reyes, Alisha W. B., Huy, Tran X. N., Arayan, Lauren T., Min, WonGi, Lee, Hu J., Rhee, Man H., Chang, Hong H., Kim, Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640714/
https://www.ncbi.nlm.nih.gov/pubmed/29062811
http://dx.doi.org/10.3389/fcimb.2017.00437