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Morbid Sequences Suggest Molecular Mimicry between Microbial Peptides and Self-Antigens: A Possibility of Inciting Autoimmunity

Understanding etiology of autoimmune diseases has been a great challenge for designing drugs and vaccines. The pathophysiology of many autoimmune diseases may be attributed to molecular mimicry provoked by microbes. Molecular mimicry hypothesizes that a sequence homology between foreign and self-pep...

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Detalles Bibliográficos
Autores principales: Pahari, Susanta, Chatterjee, Deepyan, Negi, Shikha, Kaur, Jagdeep, Singh, Balvinder, Agrewala, Javed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640720/
https://www.ncbi.nlm.nih.gov/pubmed/29062305
http://dx.doi.org/10.3389/fmicb.2017.01938