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Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope

Hantaviruses are zoonotic pathogens that cause severe hemorrhagic fever and pulmonary syndrome. The outer membrane of the hantavirus envelope displays a lattice of two glycoproteins, Gn and Gc, which orchestrate host cell recognition and entry. Here, we describe the crystal structure of the Gn glyco...

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Detalles Bibliográficos
Autores principales: Rissanen, Ilona, Stass, Robert, Zeltina, Antra, Li, Sai, Hepojoki, Jussi, Harlos, Karl, Gilbert, Robert J. C., Huiskonen, Juha T., Bowden, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640846/
https://www.ncbi.nlm.nih.gov/pubmed/28835498
http://dx.doi.org/10.1128/JVI.00378-17