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Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency

Exosomes are defined as submicron (30–150 nm), lipid bilayer-enclosed extracellular vesicles (EVs), specifically generated by the late endosomal compartment through fusion of multivesicular bodies with the plasma membrane. Produced by almost all cells, exosomes were originally considered to represen...

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Detalles Bibliográficos
Autores principales: Willis, Gareth R., Kourembanas, Stella, Mitsialis, S. Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640880/
https://www.ncbi.nlm.nih.gov/pubmed/29062835
http://dx.doi.org/10.3389/fcvm.2017.00063