Dual-Specificity Phosphatase 12 Targets p38 MAP Kinase to Regulate Macrophage Response to Intracellular Bacterial Infection

The mitogen-activated protein kinase (MAPK) cascades are activated in innate immune cells such as macrophages upon the detection of microbial infection, critically regulating the expression of proinflammatory cytokines and chemokines such as TNF-α, IL-6, and MCP-1. As a result, activation of MAPKs i...

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Detalles Bibliográficos
Autores principales: Cho, Sharol Su Lei, Han, Jian, James, Sharmy J., Png, Chin Wen, Weerasooriya, Madhushanee, Alonso, Sylvie, Zhang, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640881/
https://www.ncbi.nlm.nih.gov/pubmed/29062315
http://dx.doi.org/10.3389/fimmu.2017.01259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640881/
https://www.ncbi.nlm.nih.gov/pubmed/29062315
http://dx.doi.org/10.3389/fimmu.2017.01259

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