Curcumin Exerts Effects on the Pathophysiology of Alzheimer’s Disease by Regulating PI(3,5)P2 and Transient Receptor Potential Mucolipin-1 Expression

BACKGROUND: To validate our speculation that curcumin may ameliorate Alzheimer’s disease (AD) pathogenesis by regulating PI(3,5)P2 and transient receptor potential mucolipin-1 (TRPML1) expression levels. METHODS: We developed an animal model presenting AD by APP/PS1 transgenes. The mouse clonal hipp...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Fang, Yu, Cheng, Xuan, Lian, Ya-Jun, Xu, Hong-liang, Zeng, Zhao-Shu, Zhu, Hong-can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640884/
https://www.ncbi.nlm.nih.gov/pubmed/29062301
http://dx.doi.org/10.3389/fneur.2017.00531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640884/
https://www.ncbi.nlm.nih.gov/pubmed/29062301
http://dx.doi.org/10.3389/fneur.2017.00531

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